Cavity 18 — apo (no ligand)

TYMS dimer (apo, Phase-6c-hardened receptor). Wheat sticks: cavity-18 residues (FPocket druggability 0.994). Red sticks: residues that are *also* on the published allosteric communication loop 181–197 (Anderson 2012, Pozzi 2019). Click & drag to rotate, scroll to zoom.

Legend: grey cartoon: protein backbone wheat sticks: cavity-18 residues red sticks: allosteric loop 181-197 ∩ cavity 18
Toggle: