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C195S (holo) + top dUMP pose
Mutant C195S (raltitrexed retained (holo)). Top Vina pose of dUMP shown alongside the mutated receptor.
Receptor cartoon + transparent surface
Active-site sticks (yellow C)
dUMP (UMP — magenta sticks)
Cofactor (D16/raltitrexed — cyan sticks)
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Cartoon only
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